PDGFRA and cholangiocarcinoma: Meanwhile, there was no obvious staining signal of PDGFR-α in normal or CCA tissues, regardless of lymph node metastasis (LNM) (Supplementary Fig. 3D), and the detection of PDGFR-α and PDGFR-β in cell lines was consistent with this observation (Supplementary Fig. 3G-H).