To further evaluate the correlation between the expression level of SRPX2 and the clinical significance in patients with thyroid cancer, we found higher SRPX2 expression in all cancer stages and lymph node metastasis grades of thyroid cancer tissues than in normal tissues by using the UALCAN and GEPIA databases (http://gepia.cancer-pku.cn/index.html) (Fig. 2A-C). This evidence concerns the gene SRPX2 and cancer.