CD274 and hepatocellular carcinoma: Cox multivariate analysis showed tumor AJCC stage (OR = 11.841, 95%CI: 2.589–54.16, P = 0.001) and preoperative hepatitis (OR = 5.427, 95%CI: 1.084–27.175, P = 0.04), and the expression level of PD-L1 in paracancer tissues (OR = 7.172, 95%CI: 1.405–36.606, P = 0.018) was an independent risk factor affecting survival of patients after radical hepatoma surgery, as shown in Table 4.