CD4+T cells (r = 0.429, p = 7.90e − 17), while neutrophils (r = 0.544, p = 5.24e − 28) and dendritic cells (r = 0.464, p = 1.40e − 19) were significantly increased in HCC, were negatively correlated with tumor purity (r =  − 0.247, P = 1.40E − 19). This evidence concerns the gene CD4 and hepatocellular carcinoma.