Taken together, we have shown that METTL3 methylates EBOV mRNAs, is recruited to EBOV inclusion bodies as the sites of viral RNA synthesis, and plays an important role in viral RNA synthesis of not only EBOV but also other haemorrhagic fever-causing NSVs (i.e. JUNV and CCHFV). The gene discussed is METTL3; the disease is hemorrhagic fever.