Despite identifying five ovarian cancer patients, there was no crossover between the variants we identified in our patients with cancer and the five most common BRCA1 variants identified in the meta-analysis by Younes and Zayid [45], nor any carriers of the key Ashkenazi ‘founder’ BRCA1 and BRCA2 variants [41, 42]. Here, BRCA1 is linked to ovarian carcinoma.