TP53 and ovarian carcinoma: The BRCA1 variant c5530delC, which has been flagged as unique among Saudi Arabian ovarian cancer patients [45], and one of the most common variants observed in another Saudi Arabian ovarian cancer cohort by Agha et al. [49], was present in one subject with ovarian cancer, with each patient carrying a different variant (3 in BRCA1, 1 in APC, 1 in TP53, see Supplementary Table 3).