Experiments designed to either induce expression of ACSL4 in ACSL4-negative cells (MCF7 or SKBr3) or ablate expression in ACSL4-positive cells (MDA-MB-231) demonstrate a role for ACSL4 in stimulating proliferation, migration and invasion in breast cancer [24, 25, 52]. This evidence concerns the gene ACSL4 and breast carcinoma.