The International Prognostic Score (IPS), which includes the following risk factors (for each one present, the patient receives 1 point), allows for further risk stratification of patients: hemoglobin level: 10.5 g/dL; albumin level: 4 g/dL, male, under 45 years old, stage IV disease, white blood cell (WBC) count >15,000/L, which is a sign of leukocytosis. Here, ALB is linked to Increased total leukocyte count.