In addition, adhesion G protein-coupled receptor V1 (ADGRV1) is potentially associated with FS-related epilepsy as a susceptibility gene, encoding a very large G protein-coupled receptor-1 (VLGR1), which is localized at synaptic junctions and cooperatively regulates synaptic function (Togashi et al., 2002). This evidence concerns the gene ADGRV1 and Feingold syndrome.