GPT and hypertensive disorder: The most common grade 3/4 TEAE in the REG120 mg/80 mg group were elevated aspartate aminotransferase (AST) (23%/9%), elevated lipase (20%/5%), elevated glutamate aminotransferase (ALT) (17%/9%), and elevated hypertension (17%/9%) (21), the incidence of grade 4 drug-related adverse events was low, no treatment-related bleeding was reported, and AEs that occurred during treatment were manageable.