To further explore the effect of TXNL4A on HCC, we performed univariate and multivariate Cox regression analyses using R. The results revealed that TXNL4A could be an independent prognostic factor for HCC (univariate: HR (95% confidence interval [CI]): 1.947 (1.364–2.780), p < 0.001; multivariate: HR (95% CI): 1.833 (1.130–2.976), p = 0.014) (Table 2). Here, TXNL4A is linked to hepatocellular carcinoma.