ABL1 and Parkinson disease: It has been described that c-Abl aberrant activation induced a progressive accumulation of α-Syn in the human A53T mutant α-Syn tg mouse model of genetic PD (Brahmachari et al., 2016) through the phosphorylation at tyr39 (Mahul-Mellier et al., 2014; Brahmachari et al., 2016; Dikiy et al., 2016), thus contributing to neurodegeneration.