Hence, the differences in the accumulation of N-tr-Aβ and its pyroglutamate modified form between idiopathic autism and dupl-15 with autism (Frackowiak et al., 2020) may result from the fact that the duplicated 15q11-13 section of the human chromosome contains a cluster of three GABAA receptor subunit (GABR) genes, GABRB3, GABRA5, and GABRG3. This evidence concerns the gene GABRA5 and autism.