Among them, the genus Lachnospiraceae UCG-008 is positively correlated to the release of inflammatory factors such as IL-6, HS-CRP, and TNF-α, indicating that reducing the numbers of Lachnospiraceae UCG-008 is beneficial for controlling inflammation and can function in controlling periodontitis (Zhu et al., 2020). The gene discussed is IL6; the disease is periodontitis.