Furthermore, in a cohort of non-cancer controls and CRC patients, four zinc finger proteins (ZNF346, ZNF638, ZNF700, and ZNF768) were detected in CRC patients and adjacent normal tissues, and used as capture antigens for the detection of autoantibodies in CRC and conferred a specificity of 91.4% and sensitivity of 41.7% for the detection of cancer [24]. Here, ZNF346 is linked to cancer.