ZNF575 and neoplasm: Our results indicated that ZNF575 significantly impairs HCT116 tumor growth with a 63.6% and 58.7% inhibition in tumor volume and tumor weight, respectively (Figs. 2B–2D, tumor volume, HCT116-Control 819.97 ± 153.82 mm3vs. HCT116-ZNF575 297.41 ± 78.87 mm3; tumor weight, HCT116-Control 0.61 ± 0.09 g vs. HCT116-ZNF575 0.25 ± 0.04 g).