The purposes of the study were as follows: (1) to test whether preoperative embolization of WHOGr1 meningiomas affects the AhR signaling pathway and (2) to investigate the impact of HIF-1α and AhR inducers on HIF-1α and AhR signaling pathways and determine whether there is crosstalk between these pathways in meningioma cells. This evidence concerns the gene HIF1A and meningioma.