AKT1 and cancer: Hydrazides-hydrazones arefrequently occurring eligible motifsin druglike small molecules due to their distinctive characteristicsand several pharmaceutical applications for the treatment of manydiseases, particularly severe bacterial infections, cancer, and inflammation.14−18 Hydrazones have been reported to exert striking antitumor action via induction of apoptosis, cell cycle arrest, inhibitionof angiogenesis, and a plethora of cancer-related biological targets(e.g., Akt).19−26