Overexpression of miR-944 stimulates apoptosis and suppresses tumor cell proliferation and metastasis in HCC patients by suppressing of E-cadherin levels and inhibiting the insulin growth factor-1 receptor (IGF-1R) gene expression that stimulates the phosphatidylinositol-3 kinase and protein kinase B (PI3K/Akt) leading to very poor survival of HCC patients [16]. Here, CDH1 is linked to hepatocellular carcinoma.