MAP2K7 and neoplasm: Its possible mechanisms include: inhibiting Akt and Braf/MEK/ERK1/2 pathways to prevent cell growth and promote cell apoptosis (15); Pre acylated Ras/Raf/MEK and PI3K/Akt/mTOR signal pathways inhibit tumor endothelial cell growth (123); Increase the expression of miR-140-5p, thereby inhibiting proliferation and inducing apoptosis (12).