AKT1 and cervical carcinoma: Furthermore, in a study conducted by Dong et al. [52], in 2018, it was reported that overexpression of miR-18a in cervical cancer indicates an increase in PD-L1 levels by preventing phosphatase and tensin homolog (PTEN) (a PI3K-AKT pathway inhibitor), WNK2 (a MAPK inhibitor), and SRY-box transcription factor 6 (SOX6) (a type of Wnt/β-catenin inhibitor), activated PI3K/AKT, MAPK, and Wnt/β-catenin pathways and promoted the induction of PD-L1 [52].