CKD may lead to a reduced nutrient intake secondary to toxin accumulation, changes in satiety regulatory hormones, inflammation, the effects of peritoneal dialysis on one’s sense of fullness, nutrient depletion associated with dialysis, anemia in relation to hyporesponsiveness to erythropoietin and iron, alterations in growth hormones, and protein-energy wasting [14,39]. This evidence concerns the gene EPO and anemia.