REN and diabetes mellitus: In our work, DHS produced a lot of data on the proteomic analysis of T2DM patients' serum, reflecting the mechanisms of diabetes occurrence and development, for example the renin-angiotensin system, vitamin digestion and absorption, hypertrophic cardiomyopathy, dilated cardiomyopathy, protein digestion and absorption, adrenergic signaling in cardiomyocytes, and metabolic pathways.