CEACAM5 and neoplasm: After 8 hours of coculture at an E:T ratio of 6:1, M5A, hMN-14, and BW431/26 CAR-T cells showed diverse cytolytic activity against tumor cell lines with different levels of CEA expression: high (LoVo and LS174T) and moderate or low (HT-29, Caco-2, and MCF7) (Figure 6B).