We found that RA synovial fibroblasts when treated with sodium lactate increase their motility capabilities (Figures 3A, B); this effect was reversed by lactate transporter inhibition with phroletin suggesting that lactate-induced fibroblast motility is mediated by SLC16A1-3 (Figure 3A, B). The gene discussed is SLC16A13; the disease is rheumatoid arthritis.