With cis-eQTL instruments and stratified FDR adjustment applied, the additional associations between IL-6 (OR: 2.01, 95% CI: 1.27-3.17, P: 0.003), MIF (OR: 1.13, 95% CI: 1.04-1.22, P: 0.004) and HF, as well as FGFBasic (basic fibroblast growth factor) and AF (OR: 0.66, 95% CI: 0.5-0.84, P: 0.001) were captured. The gene discussed is IL6; the disease is hydrops fetalis.