In this study, we further explored that TTK, BUB1B, NUSAP1, and ZWINT hub genes were part of many diverse GO terms and were associated with different cancer-related signaling pathways, including “cell cycle, progesterone-mediated oocyte maturation, oocyte meiosis, cellular senesces, and viral carcinogenesis” pathways in the OC patients. Here, BUB1B is linked to cancer.