TRPV4 rs3742037, TRPM8 rs17862920 and SLC17A8 rs11110359 were associated with depression in dominant model [ORadj (95% CI): 2.03 (1.06–3.96), p = 0.035; 0.48 (0.23–0.96), p = 0.042; 0.42 (0.20–0.84), p = 0.016, respectively]. The gene discussed is SLC17A8; the disease is depressive symptom measurement.