To date, at least 10 cases of ALS complicated with FTD have been reported to be associated with VCP variants (Miller et al., 2009; Kumar et al., 2010; Johnson et al., 2010; Koppers et al., 2012; Spina et al., 2013; Hirano et al., 2015; Hirano et al., 2017; Matsubara et al., 2021). The gene discussed is VCP; the disease is frontotemporal dementia.