INS and type 2 diabetes mellitus: However, although current antidiabetic drugs, insulin therapy, and lifestyle interventions, for example, metformin administration, carbohydrate restriction, and/or endurance exercise, have warranted decent control of T2DM progression, implementing and maintaining these changes for prolonged periods are still challenging, especially given the pervasiveness of drug side‐effects and the accessibility of calorically dense foods and sedentary lifestyle.