These ceRNA/miRNA/PCG signaling axes that inhibit cancer cell apoptosis include lncTUG1/miR-1294/PLK1 [7] and circ_0004370/miR-1294/LIM and SH3 protein 1 (LASP1) [18] in EC, lncNEAT1/miR-1294/AKT1 in GC [9], circPLK1/miR-1294/HMGA1 [25] and circSHKBP1/miR-1294/PKM2 [26] in NSCLC, circCDK17/miR-1294/YWHAZ in CC [27], and CircEYA3/miR-1294/c-Myc in PDAC [17]. This evidence concerns the gene PKM and cancer.