Furthermore, they are associated with Receptor Tyrosine Kinase signaling (p = 2.36E−9), long-term potentiation (p = 2.15E−5), PI3K/AKT signaling in cancer (p = 5.82E−5), and regulation of PI3K/AKT signaling by PI5P, PP2A, and IER3 (p = 6.78E−5). The gene discussed is IER3; the disease is cancer.