Another cilia-related transcript is doublecortin-domain containing 2B (DCDC2B, increased 1.9-fold in CAD) which interacts with tubulin 2B (TUBB, increased 1.7-fold in CAD) to affect the hair cell kinocilia, and its mutation likewise leads to recessive deafness [44]. The gene discussed is CAD; the disease is deafness.