While FM, FFM, and TBW fared much worse and were solely related to the risks for stroke, BMI, followed by the WHtR and the BF%, exhibited the highest relationships with the estimated cardiovascular risk estimates. In contrast to ADMA, which showed linkages to WHtR, FFM, and TBW, and ET-1, which showed links to BMI and FM alone, levels of NT-proBNP were not connected to any measure of obesity. Here, EDN1 is linked to obesity due to melanocortin 4 receptor deficiency.