FGF23 and chronic kidney disease: However, serum creatinine alone does not adequately estimate kidney function in children, and FGF23 is not an excellent predictor of LVH in children with advanced CKD.10,18 Given the frequency of LVH in the CKD population and the effect of LVH on cardiovascular health, it is in turn crucial to discover additional biomarkers of LVH so we can better inform our understanding of the relationship between CKD and LVH and the pathophysiology of LVH.