Among those with nonglomerular disease, urine YKL-40 was associated with LVH in the unadjusted model (PR: 1.15, 95% CI, 1.03 to 1.28, interaction P value: 0.007), but not in those with glomerular disease (PR: 0.98, 95% CI, 0.95 to 1.01). The gene discussed is CHI3L1; the disease is glycogen storage disease VI.