Heat shock protein 90 alpha family class B member 1 (HSP90AB1) can promote the proliferation, migration and glycolysis of head and neck squamous cell carcinoma, and play an important role in epithelial mesenchymal transformation in the progression of gastric cancer (Zhang et al. 2022a, b; Wang et al. 2019). The gene discussed is HSP90AB1; the disease is head and neck squamous cell carcinoma.