The data from The Cancer Genome Atlas (TCGA) datasets, including 59 BRAF-mutated and 337 BRAF wild-type colon cancer patients, showed that the proportion of CD8+ T cells was significantly higher in BRAF-mutated colon cancer tissues than that in BRAF wild-type colon cancer tissues (P < 0.01) [85]. This evidence concerns the gene CD8A and malignant colon neoplasm.