Sun et al. found that intermittent parathyroid hormone treatment could maintain bone remodeling homeostasis and improve microarchitecture of subchondral bone in osteoarthritis mice, via interfering with TGF-β signaling to attenuate the recruitment and expansion of Nestin+ and Osterix+ MP in bone marrow [135]. This evidence concerns the gene TGFB1 and osteoarthritis.