These genes are involved in cholesterol metabolism (Abca1, Abcg8, Abcg5, Lpl, Cyp7a1, and Pltp), lipid and atherosclerosis (Abca1, Il1b, Ccl2, and Abcg1), bile secretion (Abcg8, Abcg5, and Cyp7a1), and IL-17 signaling pathway (Ccl7, Il1b, and Ccl2) (Table S12). The gene discussed is CYP7A1; the disease is atherosclerosis.