HOXB9 and neoplasm: In the clinical perspective, a better understanding of the specific mechanism of HOXB9 in tumorigenesis is aided by the significant correlation observed between HOXB9 and various factors, including prognosis, immune regulation, infiltration of immune cells, tumor microenvironment, tumor mutational burden (TMB), and microsatellite instability (MSI), especially when HOXB9 is expressed at high levels.