INS and endometrial cancer: Results indicated that patients in high-risk score subgroup were associated with Spliceosome signaling (NES=2, P=0.004), DNA replication signaling (NES=1.8, P=0.008), Base excision repair signaling, and Cell cycle signaling (NES=1.8, P=0.012) (Figure 7F), whereas patients in the low-risk score subgroup were linked to Adherence junction signaling (NES=-1.6, P=0.037), Lysine degradation signaling (NES=-1.6, P=0.037), Adipocytokine signaling (NES=-1.9, P=0.002), Propanoate metabolism signaling (NES=-1.8, P=0.01), Insulin signaling (NES=-1.7, P=0.002), and Endometrial cancer signaling (NES=-1.6.