In experiments in colorectal cancer tissue samples, RIOK1 phosphorylation and protein expression of KDM1A/CSNK2A1 are positively correlated with RIOK1 protein expression, whereas RIOK1 methylation is negatively correlated with protein expression of SETD7/FBXO6.10 This evidence concerns the gene CSNK2A1 and colorectal cancer.