Across 54 PCa samples, we detected 11 novel TMPRSS2 fusion partners (Linc00114, PPP3CA, AMACR, CASZ1, SIM2, TTC18, FGFR2, OPTN, C1orf61, TBXAS1, RERE) bearing 21 different breakpoint sequence (Fig.3, Table S4). Here, CASZ1 is linked to posterior cortical atrophy.