In contrast to CD44, YY2 overexpression increased the percentage of EGFP‐positive HCC‐LM3 cells transfected with PCMV‐Numb‐EGFP or PCMV‐Alb‐EGFP (Figure 3E; Figure S6E, Supporting Information); whereas YY2 knock‐out decreased them (Figure 3F; Figure S6F, Supporting Information). Here, YY2 is linked to hepatocellular carcinoma.