DRP1 overexpression restored the colocalization of DRP1 with DsRed‐Tom20 in YY2‐overexpressed HCC‐LM3 cells obtained from stem‐like tumor spheres (Figure6A); whereas DRP1 silencing abolished the increase of its level in HCC‐LM3YY2KO cells obtained from stem‐like tumor spheres (Figure 6B). This evidence concerns the gene TOMM20 and neoplasm.