YY2 and hepatocellular carcinoma: Meanwhile, knocking out YY2 in HCC‐LM3 (HCC‐LM3YY2KO) and MHCC‐97H (MHCC‐97HYY2KO) cells using CRISPR/Cas9 technology (Figure S2D,E, Supporting Information) resulted in robust upregulation of CSC markers (Figure 2B).