At multiple linear regression, while introducing age, presence of HCC, serum Mg concentration, diuretic treatment as covariates in the initial backward elimination model, the direct correlation between Δ-MELDNa and the percentage of hepatocytes with intense (B = 0.436; 95% CI of B = 0.179–0.670; p = 0.009) and with total TRPM7 staining (B = 0.153; 95% CI of B = 0.054–0.270; p = 0.025) remained significant. Here, TRPM7 is linked to hepatocellular carcinoma.