CCL20 and neoplasm: Similarly, studies by Lu et al. [281] indicate that the CCL20/CCR6 chemokine pathway may increase p38MAPK activation, associated with changes in the miRNA profile in laryngeal cancer cells; the findings confirm that CCL20/CCR6 activity was positively associated with miR-20a-5p, miR-489, and negatively associated with miR-29-3p, miR-632, and miR-1276 in laryngeal cancer tissues, and suggested miR-632 may be a tumour suppressor in laryngeal cancers.