At the same time, they had significantly higher adiponectin levels (RYGB: 9.33 μg/mL (3.85–20.42 μg/mL) vs. obesity: 4.27 μg/mL (1.87–8.30 μg/mL), adj. This evidence concerns the gene ADIPOQ and obesity due to melanocortin 4 receptor deficiency.