Furthermore, our research showed that TP53 has control over the genes related to the regulation of iron death, as depicted in Figure 3C. Hence, we attempted to target P53, and D3 has been previously reported to prevent cardiac ischemia/reperfusion mitochondrial injury and cell loss by regulating the miR30a/p53 axis [29,30]. Here, TP53 is linked to myocardial ischemia.