Amit-Vazina et al. [8] used the azaspirane 2-(3-diethylaminopropyl)-8,8-dipropyl-2-azaspiro[4.5]decane-dimaleate (atiprimod) and found that it inhibited NF-kB activity in multiple myeloma cells at 8 μM. This evidence concerns the gene NFKB1 and plasma cell myeloma.