Qtn also inhibited NADPH oxidase expression or function in a rat polycystic ovary-related IR model [109], in a Dichlorodiphenyltrichloroethane (DDT) liver toxicity model [126] and in rat cardiomyocytes with T2DM induced with a high-calorie diet and streptozocin [113]. This evidence concerns the gene FMO5 and type 2 diabetes mellitus.