TP53 and colorectal carcinoma: These studies were conducted using SW48, a CRC MSI-High p53-KRAS-WT cell line, LS411N, a CRC MSI-High p53-Mut KRAS-WT cell line, HCT 116, a CRC MSI-High p53-WT KRAS-Mut cell line, and HCT-15, a CRC MSI-High p53-KRAS-Mut cell line (Table 3).