Interleukin-6 promotes the abnormal cell growth on the epithelial tissue surface of the cervix (pancreatic intraepithelial neoplasia (PanIN), TLR-7 and TLR-8 (Toll-like receptor) expression have been shown to increase tumor cell proliferation in human pancreatic cancer and promotes chemoresistance in UICC (Union for International Cancer Control) stage 1st and 4th pancreatic cancer (Panc-1 cancer cell lines). Here, TLR8 is linked to familial pancreatic carcinoma.